生化暨生物科技研究所 -- 王朝鐘 老師
:::
王朝鐘 老師

王朝鐘教授 聯絡方式

專長介紹

學歷: 台大醫學院生化所博士

經歷:

中山醫學院醫研所副所長(1991)

學務長(1992)

醫學系生化科主任 (1988)

生化暨生物科技研究所教授兼所長(1993-2008)

研究發展處研發長 (2008-2010)

中草藥暨保健食品研究開發中心主任


專長:

癌症生化,化學預防 (肥胖,癌症,肝及心血管疾病) 保健食品研究開發


研究:

1.腫瘤促進物質之 作用及分子機轉研究

2.化學防癌物質之開發及抑制癌化之分子機轉研究

3.抗癌藥物之發展及促進癌細胞凋謝死亡之機轉研究

4.NO及其衍生物癌化作用之分子機轉研究

5.解毒基因誘導作用之調節機轉研究

6.中草藥抗癌及調節肝臟功能之開發研究

7.抑制心血管疾病天然物開發

8.機能性食品功能性成份,分析作用及機轉研究

9.糖尿病致副病變之機轉及預防研究

10.天然物調控肝臟及體脂肪之機轉

11.肥胖癌症標靶之研究

12.私校研發特色疾病化學預防物質之研究開發


聯絡: 04-24730022-11670
04-24730022-11883
E-mail:
wcj@csmu.edu.tw

學術著作目錄(近5年)

(A) REFEREED PAPER (*者為SCI) (近五年-期刊論文)

1.           

Kuei-Chuan Chan, Hsieh-Hsun Ho, Ming-Cheng Lin, Chi-Hua Yen, Chien-Ning

Huang,Hui-Pei Huang, and Chau-Jong Wang* (2014, Oct). Mulberry Water

Extracts Inhibit Atherosclerosis through Suppression of the Integrin-β3/Focal

Adhesion Kinase Complex and Downregulation of Nuclear Factor κB Signaling

in Vivo and in Vitro. Journal of Agricultural and Food Chemistry. 本人為通訊

作者.

2.           

Kuei-Chuan Chan, Hsieh-Hsun Ho, Ming-Cheng Lin, Cheng-Hsun Wu, Chien-

Ning Huang, Wen-Chun Chang, and Chau-Jong Wang (2014, Jun). Mulberry

Water Extracts Inhibit Rabbit Atherosclerosis through Stimulation of Vascular

Smooth Muscle Cell Apoptosis via Activating p53 and Regulating Both Intrinsic

and Extrinsic Pathways. Journal of Agriculture and Food Chemistry, 62,5092-

5101. 本人為通訊作者.

3.           

Mon-Yuan Yang , Chau-Jong Wang , Nai-Fang Chen , Wen-Hsin Ho , Fung-Jou

Lu , Tsui-Hwa Tseng (2014, Apr). Luteolin enhances paclitaxel-induced

apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3.

Chemico-Biological Interactions, 213 ,60–68. 本人為第一作者.

4.           

Chang-Chieh Tang, Wea-Lung Lin,Yi-Ju Lee, Yu-Chi Tanga and Chau-Jong

Wang (2014, Mar). Polyphenol-rich extract of Nelumbo nucifera leaves inhibits

alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and antiinflammation

in C57BL/6J mice. Food Funct., 2014, , 5, 678–687. 本人為通訊

作者.

5.           

Chung-Chia Liao, Ting-Tsz Ou,b Hui-Pei Huang and Chau-Jong Wang (2014,

Mar). The inhibition of oleic acid induced hepatic lipogenesis and the promotion

of lipolysis by caffeic acid via up-regulation of AMP-activated kinase. Journal

of Science of Food and Agriculture , 94,1154–1162. 本人 為通訊作者.

6.           

Hong-Chou Chang, Chiung-Huei Peng, Da-Ming Yeh, Erl-Shyh Kao and Chau-

Jong Wang (2014, Mar). Hibiscus sabdariffa extract inhibits obesity and fat

accumulation, and improves liver steatosis in humans. Food and Function ,

5,734-739. 本人為通訊作者.

7.           

Cheng-Hsun Wu,Ting-Tsz Ou,Chun-Hua Chang, Xiao-Zong Chang,Mon-Yuan

Yang,and Chau-Jong Wang* (2014, Feb). The Polyphenol Extract from Sechium

edule Shoots InhibitsLipogenesis and Stimulates Lipolysis via Activation of

AMPK Signalsin HepG2 Cells. J. Agric. Food Chem. , 62, 750-759. 本人為通訊

作者.

8.           

 

Mu-Jang Lee , Shao-Hsuan Kao , Jing-En Hunag , Gwo-Tarng Sheu , Chi-Wei

Yeh , You-Cheng Hseu , Chau-Jong Wang, Li-Sung Hsu (2014, Feb). Shikonin

time-dependently induced necrosis or apoptosis in gastric cancer cells via

generation of reactive oxygen species. Chemico-Biological Interactions, 211 ,

44–53. 本人為通訊作者.

9.           

Tsung-Chang Tsai, Hui-Pei Huang,Yun-Ching Chang, and Chau-Jong Wang*

(2014, Feb). An Anthocyanin-Rich Extract from Hibiscus sabdariffa

LinnaeusInhibits N-Nitrosomethylurea-

10.       

Chung-Chia Liao, Ting-Tsz Ou, Cheng-Hsun Wu, and Chau-Jong Wang (2013,

Oct). Prevention of Diet-Induced Hyperlipidemia and Obesity by Caffeic Acid in

C57BL/6 Mice through Regulation of Hepatic Lipogenesis Gene Expression. J.

Agric. Food Chem, 61,11082-11088. 本 人為通訊作者.

11.       

Chang-Chieh Tang, Hui-Pei Huang , Yi-Ju Lee , Yu-Hsien Tang, Chau-Jong

Wang (2013). Hepatoprotective effect of mulberry water extracts on ethanolinduced

liver injury via anti-inflammation and inhibition of lipogenesis in

C57BL/6J mice.. Food and Chemical Toxicology, 62,786-796. 本人為通 訊作者.

12.       

Cheng-Hsun Wu, Shu-Chun Chen, Ting-Tsz Ou; Yu-Ching Chang, Charng-

Cherng Chyau, Chau-Jong Wang (2013). Mulberry leaf polyphenol extracts

reduced hepatic lipid accumulation involving regulation of adenosine

monophosphate activated protein kinase and lipogenic enzymes. JOURNAL OF

FUNCTIONAL FOODS, 5,1620-1632. 本人為通訊作者.

13.       

Chi-Nan Hung, Hui-Pei Huang,Chong-Kuei Lii, Kai-Li Liu, Chau-Jong Wang

(2013). Sulforaphane inhibits smooth muscle cell proliferation and migration by

reducing MMP-9 activity via the Ras and RhoA/ROCK pathways. JOURNAL

OF FUNCTIONAL FOODS, 5,1097-1107. 本人為 通訊作者.

14.       

Chiung-Huei Peng, Hong-Chou Chang, Mon-Yuan Yang, Chien-Ning Huang,

Shing-Jung Wang, Chau-Jong Wang (2013). Oat attenuate non-alcoholic fatty

liver and obesity via inhibiting lipogenesis in high fat-fed rat. JOURNAL OF

FUNCTIONAL FOODS, 5, 53-61. 本人為通訊作者.

15.       

Hong-Chou Chang, Chien-Ning Huang, Da-Ming Yeh, Shing-Jung Wang,

Chiung-Huei Peng, Chau-Jong Wang (2013). Oat prevents obesity and

abdominal fat distribution, and improves liver function in humans. Plant Foods

for Human Nutrition, 68, 18-23. 本人為通訊作者.

16.       

Hsieh-Hsun Ho, Chi-Sen Chang, Wei-Chi Ho, Sheng-You Liao, Wea-Lung Lin,

Chau-Jong Wang (2013). Gallic acid inhibits gastric cancer cells metastasis and

invasive growth via increased expression of RhoB, downregulation of

AKT/small GTPase signals and inhibition of NF-κB activity. TOXICOLOGY

AND APPLIED PHARMACOLOGY, 266, 76-85. 本人為通訊作者.

17.       

Hui-Pei Huang, Ting-Tsz Ou, Chau-Jong Wang (2013). Mulberry and its

Bioactive Compounds, the Chemoprevention Effects and Molecular Mechanisms

In vitro and In vivo.. Journal of Traditional and Complementary Medicine , 3,7-

15.. 本人為通訊作者.

18.       

Jia-Jen Chang, Man-Jung Hsu, Hui-Pei Huang, Dai-Jung Chung, Yun-Ching

Chang, Chau-Jong Wang (2013). Mulberry anthocyanins inhibit oleic acid

induced lipid accumulation by reduction of lipogenesis and promotion of hepatic

lipid clearance. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY ,

61,6069-6076. 本人為通訊作

19.       

Jing-Hsien Chen, Chau-Jong Wang, Chi-Ping Wang, Jenn-Yuan Sheu, Chia-

Liang Lin,Hui-Hsuan Lin (2013). Hibiscus sabdariffa leaf polyphenolic extract

inhibits LDL oxidation and foam cell formation involving up-regulation of

LXRa/ABCA1 pathway. FOOD CHEMISTRY , 141, 397–406.

20.       

Kuei-Chuan Chan, Ming-Cheng Lin, Chien-Ning Huang, Wen-Chun Chang,

Chau-Jong Wang (2013). Mulberry 1-deoxynojirimycin pleiotropically inhibits

glucose-stimulated vascular smooth muscle cell migration by activation of

AMPK/RhoB and downregulation of FAK.. J. Agric Food Chem, 61(41):9867-

9875. 本人為通訊作者.

21.       

Kuei-Chuan Chan, Mon-Yuan Yang, Ming-Cheng Lin, Yi-Ju Lee, Wen-Chun

Chang, Chau-Jong Wang (2013). Mulberry leaf extract inhibits the development

of atherosclerosis in cholesterol-fed rabbits and in cultured aortic vascular

smooth muscle cells. JOURNAL OF AGRICULTURAL AND FOOD

CHEMISTRY , 61, 2780-2788. 本人為通訊作者.

22.       

Ming-Ju Hsieh, Te-Lung Tsai, Yih-Shou Hsieh, Chau-Jong Wang, Hui-Ling

Chiou (2013). Dioscin-induced autophagy mitigates cell apoptosis through

modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung

cancer cell lines. ARCHIVES OF TOXICOLOGY , 87,1927-1937. 本人 為通訊作

.

23.       

Ting-Tsz Ou, Chih-Yi Kuo, Charng-Cherng Chyau, Huei-Jane Lee, Jih-Shin

Peng, Chau-Jong Wang (2013). Improvement of lipopolysaccharide-induced

hepatic injuries and inflammation with mulberry extracts. JOURNAL OF THE

SCIENCE OF FOOD AND AGRICULTURE, 93, 1880-1886. 本人為通訊 作者.

24.       

Ting-Tsz Ou, Ming-Cheng Lin, Wea-Lung Lin, Cheng-Hsun Wu, Chau-Jong

Wang (2013). Galic acid attenuates Oleic acid-induced proliferation of vascular

smooth muscle cell A7r5 through G2/M cell cycle arrest via the regulation

AMPK-eNOS-FAS signaling. CURRENT MEDICINAL CHEMISTRY, 20,3944-

3953. 本人為通訊作者.

25.       

Yi-Sun Yang, Chau-Jong Wang, Chien-Ning Huang, Mu-Lin Chen (2013).

Polyphenols of Hibiscus sabdariffa improved diabetic nephropathy via

attenuating renal epithelial mesenchymal transition.. J. Agric Food Chem, 61,

7545-7551.

26.       

Yi-Sun Yang, Chien-Ning Huang, Chau-Jong Wang, Yi-Ju Lee, Mu-Lin Chen,

Chiung-Huei Peng (2013). Polyphenols of Hibiscus sabdariffa improved diabetic

nephropathy via regulating the pathogenic markers and kidney functions of type

2 diabetic rats. JOURNAL OF FUNCTIONAL FOODS , 5, 810-819.

27.       

Chao-Hsin Lee, Chih-Yi Kuo, Chau-Jong Wang, Chi-Ping Wang, Yi-Ru Lee,

Chi-Nan Hung, Huei-Jane Lee (2012). A polyphenol extract of Hibiscus

sabdariffa L. ameliorates acetaminophen-induced hepatic steatosis by attenuating

the mitochondrial dysfunction in vivo and in vitro. BIOSCIENCE

BIOTECHNOLOGY AND BIOCHEMISTRY, 76, 646-651.

28.       

Chin-Yi Kuo, Erl-Shyh Kao, Kuei-Chuan Chan, Huei-Jane Lee, Tsai-Feng

Huang, Chau-Jong Wang (2012). Hibiscus Sabdariffa L. extracts reduce serum

uric acid levels in oxonate-induced rats. JOURNAL OF FUNCTIONAL FOODS,

4, 375-381. 本人為通訊作者.

29.       

Hui-Hsuan Lin, Kuei-Chuan Chan, Jenn-Yuan Sheu, Shu-Wen Hsuan, Chau-Jong

Wang, Jing-Hsien Chen (2012). Hibiscus Sabdariffa leaf induces apoptosis of

human prostate cancer cells in vitro and in vivo. FOOD CHEMISTRY, 132, 880-

891. 本人為通訊作者.

30.       

Hui-Pei Huang, Chau-Jong Wang, Jen-Pi Tsai, Sheng-Wen Wu, Tung-Wei Hung,

Jong-Da Lian, Horng-Rong Chang (2012). Y27632 attenuates the aristolochic

acid-promoted invasion and migration of human urothelial cancer TSGH cells in

vitro and inhibits the growth of xenografts In vitro. NEPHROLOGY DIALYSIS

TRANSPLANTATION , 27, 565-575.

31.       

Kuei-Chuan Chan, Cheng-Hsun Wu, Chien-Ning Huang, Kuang-Ping Lan, Wen-

Chun Chang, Chau-Jong Wang (2012). Simvastatin inhibits glucose-stimulated

vascular smooth muscle cell migration involving increased expression of RhoB

and a block of Ras/Akt signal. Cardiovascular Therapeutics , 30, 75-84. 本人為

通訊作者.

32.       

Li-Sung Hsu, Hsieh-Hsun Ho, Ming-Cheng Lin, Charng-Cherng Chyau, Jih-Shin

Peng, Chau-Jong Wang (2012). Mulberry water extracts (MWEs) ameliorated

carbon tetrachloride-induced liver damages in rat. FOOD AND CHEMICAL

TOXICOLOGY, 50, 3086-3093. 本人為通訊 作者.

33.       

Ting-Tsz Ou, Chih-Yi Kuo, Charng-Cherng Chyau, Huei-Jane Lee, Jih-Shin

Peng, Chau-Jong Wang (2012). Improvement of lipopolysaccharides-induced

hepatic injuries and inflammation with mulberry extracts. JOURNAL OF THE

SCIENCE OF FOOD AND AGRICULTURE, In press. 本人為通訊作者.

34.       

Tzi-Peng Yang, Huei-Jane Lee, Ya-Ju Chang, Chau-Jong Wang (2012). Mulberry

leaf polyphenols extract (MLPE) induced apoptosis involving regulation of

AMPK/FASN in p53-negative hepatocellular carcinoma cell. JOURNAL OF

AGRICULTURAL AND FOOD CHEMISTRY , 60, 6891-6898. 本人為通訊 作者.

35.       

Yun-Ching Chang, Jeng-Dong Hsu, Wea-Lung Lin, Yi-Ju Lee, Chau-Jong Wang

(2012). High incidence of acute promyelocytic leukemia specifically induced by

N-nitroso-N-methylurea (NMU) in Sprague-Dawley rats. ARCHIVES OF

TOXICOLOGY, 86, 315-327. 本人為通訊作者.

36.       

Cheng-Hsun Wu, Ming-Cheng Lin, Hsueh-Chun Wang, Mon-Yuan Yang, Ming-

Jia Jou, Chau-Jong Wang (2011). Rutin inhibits oleic acid induced lipid

accumulation via reducing lipogenesis and oxidative stress in hepatocarcinoma

cells. JOURNAL OF FOOD SCIENCE , 76, 65-72. 本人為通訊作者.

37.       

Chih-Yi Kuo, Cheng-Teng Hsu, Cheng-Shiao Ho, Ting-En Su, Ming-Hsun Wu,

Chau-Jong Wang (2011). Accuracy and precision evaluation of seven selfmonitoring

blood glucose systems. Diabetes Technology & Therapeutics , 13,

596-600. 本人為通訊作者.

38.       

Chiung-Huei Peng, Charng-Cherng Chyau, Kuei-Chuan Chan, Tsung-Hsien

Chan, Chau-Jong Wang, Chien-Ning Huang (2011). Hibiscus sabdariffa

polyphenolic extract inhibits hyperglycemia, hyperlipidemia, and glycationoxidative

stress while improving insulin resistance. JOURNAL OF

AGRICULTURAL AND FOOD CHEMISTRY , 59, 9901-9909. 本人為通訊 作者.

39.       

Chiung-Huei Peng, Li-Kaung Liu, Chao-Ming Chuang, Charng-Cherng Chyau,

Chieng-Ning Huang, Chau-Jong Wang (2011). Mulberry water extracts possess

an anti-obesity effect and ability to inhibit hepatic lipogenesis and promote

lipolysis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 59,

2663-2671. 本人為通訊作者.

40.       

Haw-Wen Chen, Ai-Hsuan Lin, Hsing-Chin Chu, Chien-Chun Li, Chia-Wen

Tsai, Che-Yi Chao, Chau-Jong Wang, Chong-Kuei Lii Kai-Li Liu (2011).

Inhibition of TNF-α-induced inflammation by andrographolide via downregulation

of the PI3K/Akt signaling pathway. JOURNAL OF NATURAL

PRODUCTS, 74, 2408-2413.

41.       

Hsueh-Chun Wang, Chia-Hung Hung, Jeng-Dong Hsu, Mon-Yuan Yang, Shing-

Jung Wang, Chau-Jong Wang (2011). Inhibitory effect of whole oat on aberrant

crypt foci formation and colon tumor growth in ICR and BALB/c mice.

JOURNAL OF CEREAL SCIENCE , 53, 73-77. 本人為通訊作者.

42.       

Hui-Hsuan Lin, CW Tsai, Fen-Pi Chou, Chau-Jong Wang, Jing-Hsien Chen

(2011). Andrographolide down-regulates hypoxia-inducible factor-1α in human

non-small cell lung cancer A549 cells. TOXICOLOGY AND APPLIED

PHARMACOLOGY, 250, 336-345.

43.       

Hui-Hsuan Lin, Jing-Hsien Chen, Chau-Jong Wang (2011). Chemopreventive

properties and molecular mechanisms of the bioactive compounds in Hibiscus

Sabdariffa Linne. CURRENT MEDICINAL CHEMISTRY, 18, 1245-1254. 本人為

通訊作者.

44.       

Hui-Hsuan Lin, Jing-Hsien Chen, Feu-Pi Chou, Chau-Jong Wang (2011).

Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation

of Ras/Akt/ NF-κB pathway and MMP-2 production by targeting RhoB

activation. BRITISH JOURNAL OF PHARMACOLOGY , 162, 237-254. 本人為

通訊作者.

45.       

Hui-Pei Huang, Yun-Ching Chang, Cheng-Hsun Wud, Chi-Nan Hung, Chau-

Jong Wang (2011). Anthocyanin-rich Mulberry extract inhibit the gastric cancer

cell growth in vitro and xenograft mice by inducing signals of p38/p53 and c-jun.

FOOD CHEMISTRY , 129, 1703-1709. 本人為通訊 作者.

46.       

Jen-Dong Hsu, Shao-Hsuan Kao, Ting-Tsz Ou, Yu-Jen Chen, Yi-Ju Li, Chau-

Jong Wang (2011). Gallic acid Induces G2/M phase arrest of breast cancer cell

MCF-7 through stabilization of p27(Kip1) attributed to disruption of

p27(Kip1)/Skp2 complex. JOURNAL OF AGRICULTURAL AND FOOD

CHEMISTRY , 59, 1996-2003. 本人為通訊作者.

47.       

Jiaan-Der Wang, Te-Kau Chang, Heng-Kueix Lin, Fang-Liang Huang, Chau-

Jong Wang, Huei-Jane Li (2011). Reduced expression of transforming growth

factor-β1 and correlated elevation of interleukin-17 and interleukin-γ in Pediatric

patients with chronic primary immune thrombocytopenia. PEDIATRIC BLOOD

& CANCER , 57, 636-640.

48.       

Mon-Yuan Yang, Chien-Ning Huang, Kuei-Chuan Chan, Yi-Sun Yang, Chiung-

Huei Peng, Chau-Jong Wang (2011). Mulberry leaf polyphenols possess

antiatherogenesis effect via inhibiting LDL oxidation and foam cell formation.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 59, 1985-1995.

人為通訊作者.

49.       

Mon-Yuan Yang, Yun-Ching Chang, Kuei-Chuan Chan, Yi-Ju Lee, Chau-Jong

Wang (2011). Flavonoid-enriched extracts from Nelumbo nucifera leaves inhibits

proliferation of breast cancer in vitro and in vivo. European Journal of

Integrative Medicine , 153-163. 本人為通訊作者.

50.       

Mu-Jang Lee, Han-Min Chen, Bor Show Tzang, Chiu-Wen Lin, Jer-Yuh Liu,

Chau-Jong Wang, Shao-Hsuan Kao (2011). Ocimum gratissimum aqueous

extract protects H9c2 myocardiac cells from H2O2-induced cell apoptosis

through Akt signalling. Evidence-based Complementary and Alternative

Medicine , In Press.

51.       

Ting-Tsz Ou, Cheng-Hsun Wu, Jeng-Dong Hsu, Charng-Cherng Chyau, Huei-

Jane Li and Chau-Jong Wang (2011). Paeonia lactiflora Pall inhibits bladder

cancer growth involving phosphorylation of Chk2 in vitro and in vivo.

JOURNAL OF ETHNOPHARMACOLOGY , 135, 162-172. 本人為通訊作者.

52.       

Ting-Tsz Ou, Man-Jung Hsu, Kuei-Chuan Chan, Chieng-Ning Huang, Hsieh-

Hsun Ho, Chau-Jong Wang (2011). Mulberry inhibits oleic acid-induced lipid

accumulation via reduction of lipogenesis and promotion of hepatic lipid

clearance. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE , 91,

2740-2748. 本人為通訊作者.

53.       

Cheng-Hsun Wu, Mon-Yuan Yang, Kuei-Chuan Chan, Pei-Jun Cheng, Ting-Tsz

Ou, Chau-Jong Wang (2010). Improvement in high-fat diet-induced obesity and

body fat accumulation by a Nelumbo nucifera leaf flavonoid-rich extract in mice.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 58, 7075-7081.

人為通訊作者.

54.       

Cheng-Hsun Wu, Yuan-Wei Shin, Chun-Hua Chang, Ting-Tsz Ou, Chi-Chou

Huang, Jeng-Dong Hsu, Chau-Jong Wang (2010). EP4 upregulation of ras

signaling and feedback regulation of ras in human colon tisues and cancer cells.

ARCHIVES OF TOXICOLOGY, 84, 731-740. 本人為通訊作者.

55.       

Chia-Wen Lo, Hui-Pei Huang, Kuei-Chuan Chan, Cheng-Hsun Wu, Chau-Jong

Wang (2010). Hibiscus sabdariffa extract induced apoptosis of proliferating

smooth muscle cell. JOURNAL OF FOOD BIOCHEMISTRY , 34, 549-563. 本人

為通訊作者.

56.       

Horng-Rong Chang, Hui-Pei Huang, Yu-Lin Kao, Sung-Lang Chen, Sheng-Wen

Wu, Tung-Wei Hung, Jong-Da Lian, Chau-Jong Wang (2010). The suppressive

effect of Rho kinase inhibitor, Y-27632, on oncogenic Ras/RhoA induced

invasion/ migration of human bladder cancer TSGH cells. CHEMICOBIOLOGICAL

INTERACTIONS , 83, 172-180. 本人為通訊作者.

57.       

Hsieh-Hsun Ho, Chi-Sen Chang, Wei-Chi Ho, Sheng-You Liao, Cheng-Hsun

Wu, Chau-Jong Wang (2010). Anti-metastasis Effects of Gallic Acid on Gastric

Cancer Cells Involves inhibition of NF-κB activity and downregulation of

PI3K/AKT/small GTPase signals. FOOD AND CHEMICAL TOXICOLOGY, 48 ,

2508-2516. 本人為通訊作者.

58.       

Hsieh-Hsun Ho, Li-Sung Hsu, Kuei-Chuan Chan, Hsiang-Mei Chen, Cheng-

Hsun Wu, Chau-Jong Wang (2010). Extract from the leaf of nucifera reduced the

development of atherosclerosis via inhibition of vascular smooth muscle cell

proliferation and migration. FOOD AND CHEMICAL TOXICOLOGY, 48, 159-

168. 本人為通訊作者.

59.       

Hsueh-Chun Wang, Dun-Hao Wu, Yun-Ching Chang, Yi-Ju Li, Cheng-Hsun Wu,

Chau-Jong Wang (2010). Solanum nigrum Linn. water extract inhibits metastasis

in mouse melanoma cells in vitro and in vivo. JOURNAL OF AGRICULTURAL

AND FOOD CHEMISTRY , 58, 11913-11923. 本人為 通訊作者.

60.       

Hsueh-Chun Wang, Pei-Jun Chung, Cheng-Hsun Wu, Kuang-Ping Lan, Mon-

Yuan Yang, Chau-Jong Wang (2010). Solanum nigrum L. polyphenolic extract

inhibits hepatocarcinoma cell growth by inducing G2/M phase arrest and

apoptosis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 91,

178-185. 本人為通訊作者.

61.       

Huei-Jane Lee, Chang-Che Chen, Chau-Jong Wang (2010). Water extracts from

Neulumbo nucifera leaf reduced plasma lipids and atherosclerosis in cholesterol

fed rabbits. JOURNAL OF FOOD BIOCHEMISTRY , 34, 779-795. 本人為通訊

作者.

62.       

Hui-Hsuan Lin, Jing-Hsien Chen, Chau-Jong Wang (2010). Chemopreventive

properties and molecular mechanisms of the bioactive compounds in Hibiscus

Sabdariffa Linne. CURRENT MEDICINAL CHEMISTRY , 18, 1245-1254. 本人

為通訊作

63.       

Jiaan-Der Wang, Ting-Tsz Ou, Wei-Chi Ho, Chau-Jong Wang, Te-Kau Chang,

Huei-Jane Lee (2010). Platelet apoptosis resistance and increased CXCR4

expression in pediatric patients with chronic immune thrombocytopenic purpura.

THROMBOSIS RESEARCH , 126, 311-318. 本人為通訊作者.

64.       

Kuei-Chuan Chan, Hsieh-Hsun Ho, Chiung-Huei Peng, Kuang-Ping Lan, Ming-

Cheng Lin, Hsiang-Mei Chen, Chau-Jong Wang (2010). Polyphenol-rich extract

from mulberry leaf inhibits vascular smooth muscle cell proliferation involving

upregulation of p53 and inhibition of Cyclin-Dependent Kinase. JOURNAL OF

AGRICULTURAL AND FOOD CHEMISTRY , 58, 2536-2542. 本人為通訊 作者.

65.       

Liang-Chih Liu, Chau-Jong Wang, Ching-Chih Lee, Sheng-Chi Su, Huei-Lin

Chen, Jen-Dong Hsu, Huei-Jane Lee (2010). Aqueous extract of Hibiscus

sabdariffa L. decelerates acetaminophen-induced acute liver damage by reducing

cell death and oxidative stress in mouse experimental models. JOURNAL OF

THE SCIENCE OF FOOD AND AGRICULTURE , 90, 329-337.

66.       

Mon-Yuan Yang, Chiung-Huei Peng, Kuei-Chuan Chan, Yi-Sun Yang, Chien-

Ning Huang, Chau-Jong Wang (2010). The hypolipidemic effect of Hibiscus

sabdariffa polyphenols via inhibiting the lipogenesis and promoting the hepatic

lipid clearance. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY ,

58, 850-859. 本人為通訊作者.

67.       

Mon-Yuan Yaug, Li-Sung Hsu, Chung-Huei Peng, Yi-Ju Li, Yuan-Shong Shi,

Cheng-Hsun Wu, Chau-Jong Wang (2010). Polyphenol-rich extracts from

Solanum nigrum attenuated PKC alpha-mediated migration and invasion of

hepatocellular carcinoma cells. JOURNAL OF AGRICULTURAL AND FOOD

CHEMISTRY , 58, 5806-5814. 本人為通訊作者.

68.       

Ting-Tsz Ou, Chau-Jong Wang, Yung-Shu Lee, Cheng-Hsun Wu, Huei-Jane Lee

(2010). Gallic acid induces G2/M phase cell cycle arrest via regulating 14-3-3β

release from Cdc42 and Chk2 activation in human bladder transitional carcinoma

cells. MOLECULAR NUTRITION & FOOD RESEARCH , 54, 1781-1790. 本人

為通訊作者.

69.       

Tzi-Peng Yang, Hui-Ling Chiou, Ming-Chei Maa, Chau-Jong Wang (2010).

Mithramycin inhibits human epithelial carcinoma cell proliferation and migration

involving downregulation of Eps8 expression. CHEMICO-BIOLOGICAL

INTERACTIONS , 183, 181-186. 本人為通訊作者.

70.       

Yi-Chieh Lee, Hui-Hsuan Lin, Chin-Hsun Hsu, Chau-Jong Wang, Tai-An

Chiang, Jing-Hsieh Chen (2010). Inhibitory effects of andrographolide on

migration and invasion in human non-small cell lung cancer A549 cells via

down-regulation of PI3K/Akt signaling pathway. EUROPEAN JOURNAL OF

PHARMACOLOGY , 632, 23-32. 本人為通訊作者.

71.       

Chien-Ning Huang, Kuei-Chuan Chan, Wei-Ting Lin,Shi-Li Su, Chau-Jong

Wang, Chiung-Huei Peng (2009). Hibiscus sabdariffa inhibits vascular smooth

muscle cell proliferation and migration induced by high glucose---amechanism

involves connective tissue growth factor signals. JOURNAL OF

AGRICULTURAL AND FOOD CHEMISTRY , 57, 3073-3079. 本人為通訊 作者.

72.       

Erl-Shyh Kao, Jeng-Dong Hsu, Chau-Jong Wang, Su-Huei Yang, Su-Ya Cheng,

Huei-Jane Lee (2009). Polyphenols extracted from Hibiscus sabdariffa L.

inhibited lipopolysaccharide-induced inflammation by improving antioxidative

conditime and regulating cyclooxygenase-2 expression. BIOSCIENCE

BIOTECHNOLOGY AND BIOCHEMISTRY, 73, 385-390.

73.       

Erl-Shyh Kao, Tsui-Hwa Tseng, Huei-Jane Lee, Kuei-Chuan Chan, Chau-Jong

Wang (2009). Anthoyanin extracts from Hibiscus attenuate oxidized LDL -

mediated foam cell formation involving regulation of CD36 gene. CHEMICOBIOLOGICAL

INTERACTIONS , 179, 212-218. 本人為通訊作者.

74.       

Hui-Pei Huang, Yuan-Wei Shih, Cheng-Hsun Wu, Po-Ju Lai, Chi-Nan Hung,

Chau-Jong Wang (2009). Inhhibitory effect of penta-acetyl geniposide on C6

glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression

involved in both the PI3K and ERK signaling pathways. CHEMICOBIOLOGICAL

INTERACTIONS , 181, 8-14. 本人為通訊作者.

75.       

Jeng-Dong Hsu, Shao-Hsuan Kao, Chang-Che Tu, Yi-Ju Li, Chau-Jong Wang

(2009). Solanum nigrum L extract inhibits 2-acetylaminofluorene-induced

hepatocarcinogenesis through overexpression of glutathione S-trausferase and

antioxidant enzymes. JOURNAL OF AGRICULTURAL AND FOOD

CHEMISTRY , 57, 8628-8634. 本人為通訊作者.

76.       

Kuei-Chuan Chan, Hsieh-Hsun Ho, Chien-Ning Huang, Ming- Cheng Lin,

Hsiang-Mei Chen, Chau-Jong Wang (2009). Mulberry leaf extract inhibits

vascular smooth muscle cell migration involving a block of small GTPase and

Akt/NF-κB signals. JOURNAL OF AGRICULTURAL AND FOOD

CHEMISTRY , 57, 9147-9153. 本人為通訊作者.

77.       

Li-Kaung Liu, Fen-Pi Chou, Yi-Chen Chen , Charny-Cherng Chyau, Hsieh-Hsun

Ho, Chau-Jong Wang (2009). Effect of Mulberry extracts on lipid hemeostasis in

vitro and in vivo. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY ,

57, 7605-7611. 本人為通訊 作者.

78.       

Ming-Cheng Lin, Shao-Hsuan Kao, Pei-Jun Chung, Kuei-Chuan Chan, Mon-

Yuan Yang, Chau-Jong Wang (2009). Improvement for high fat diet-induced

hepatic injuries and oxidative stress by feavonoid-enriched extract from

Nelumbo nucifera leaf. JOURNAL OF AGRICULTURAL AND FOOD

CHEMISTRY , 57, 5925-5932. 本人為通訊作者.

79.       

Shou-Chieh Wang, Shiow-Fen Lee, Chau-Jong Wang, Chao-Hsin Lee, Wen-Chin

Lee, Huei-Jane Lee (2009). Aqueous extract from Hibiscus sabdariffa Linnaeus

ameliorate diabetic nephropathy via regulating oxidative status and Akt/Bad/14-

3-3γ in an experimental animal model. Evidence-based Complementary and

Alternative Medicine , 1-9. 本人為通訊作者.

80.       

Ting-Tsz Ou, Chau-Jong Wang, Guang-Uei Hung, Cheng-Hsun Wu, Huei- Jane

Lee (2009). Aqueous extract of Shi-Liu-Wei-Liu-Qi-Yin induces G2/M phase

arrest and apoptosis in human bladdercarcinoma cell via Fas and mitochondria

pathway. Evidence-based Complementary and Alternative Medicine , 1-9. 本人

為通訊作者.

81.       

Wen-Chin Lee, Chau-Jong Wang, Yu-Hsin Chen, Jen-Dong Hsu, Su-Ya Cheng,

Hong-Chen Chen, Huei-Jane Lee (2009). Polyphenol extracts from Hibiscus

sabdriffa Linnaeus attenuate nephropathy in experimental type I dibetes.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 57, 2206-2210.

人為第一作者.

(B) CONFERENCE PAPER

1.       

Hui-Ting Lin, Mong-Yun Yang Chau-Jong Wang (2014, Mar). Mulberry leaf

extract inhibit HFD-induced heapatic stetosis in rats. The 29th Joint Annual

Conference of Biomedical Science, Taipei. 本人為通訊作者.

2.       

Zhi-Hong Liou,Mon-Yuan Yang,Chau-Jong Wang (2014, Mar). The extracts of

mulberry leaves exhibt potent anti-inflammation effects in the liver of rat. The

29th Joint Annual Conference of Biomedical Science, Taipei. 本人為通訊作者.

3.       

Tzu-Hsin Chen, Mon-Yuan Yang, Chau-Jong Wang (2013, Nov). Flavonoid-rich

extract from Nelumbo Nucifera leave inhibits hepatic tumorigenesis in vitro and

in vivo. International conference and exhibition on nutraceuticals and functional

foods, Taipei. 本人為通訊作者.

4.       

Bo-Han Wen, Horng-Rong Chang, Jia-Jen Chang, Chau-Jong Wang, Hui-Pei

Huang (2013, Nov). Mulberry leave extracts inhibit type ΙΙ diabetic nephropathy.

2013, International conference and exhibition on nutraceuticals and functional

foods. International conference and exhibition on nutraceuticals and functional

foods, Taipei.

5.       

Huei-Jane Lee, Hui-Pei Huang, Chau-Jong Wang (2013, Nov). The

chemoprevention effects and molecular mechanisms of mulberry (Sang Shen Zi).

International conference and exhibition on nutraceuticals and functional foods,

Taipei. 本人為通訊作者.

6.       

Hui-Ting Lin, Chau-Jong Wang, Yun-Ching Chang (2013, Nov). Hibiscus

anthocyanins inhibit N-nitrosomethylurea-induced leukemia in rats..

International conference and exhibition on nutraceuticals and functional foods,

Taipei.

7.       

Jia-Jen Chang, Man-Jung Hsu, Chau-Jong Wang, Hui-Pei Huang (2013, Nov).

Mulberry polyphenol extracts inhibit lipid accumulation by reduction of

lipogenesis and promotion of hepatic lipid clearance. . International conference

and exhibition on nutraceuticals and functional foods, Taipei. 本人為通訊作者.

8.       

Pin-Yi Hou, Chau-Jong Wang, Hui-Pei Huang (2013, Nov). Effect of Myrciaria

cauliflora extract on high-fat diet-induced obesity and hyperlipidemia in rat.

International conference and exhibition on nutraceuticals and functional foods,

Taipei.

9.       

Chang-Chieh Tang, Yu-Hsieh Tang, Mon-Yuan Yang, Chau-Jong Wang (2013).

Nelumbo nucilfera leaf extract attenuate ethanol-induced liver injury and obesity

via anti-oxidative stress and inhibiting lipogenesis in C57BL/6J mice . The 28th

Joint Annual Conference of Biomedical Science. 本人為通訊作者.

10.   

Ching-Chun Chen, Chun-Hua Chang, Chau-Jong Wang (2013). Anti-metastatic

effect of H. polyphenol-rich extracts (HPE) on human colon cancer cell via

CD44/MET signal pathway . The 28th Joint Annual Conference of Biomedical

Science . 本人為通訊作者.

11.   

Meng-Hsun Yu, Mon-Yuan Yang, Chau-Jong Wang (2013). Nnucilfera leaves

extract inhibits adipocytes-induced breast cancer metastasis . The 28th Joint

Annual Conference of Biomedical ScienceNelumbo . 本人為通訊作者.

12.   

Mon-Yuan Yang, Yun-Chia Hung, Chau-Jong Wang (2013). The flavonoid-rich

extract from Nelumbo nucifera leave inhibited fatty liver of type II diabetes

mellitus . The 28th Joint Annual Conference of Biomedical Science. 本人為通訊

作者.

13.   

Tzu-Hsin Chen, Mon-Yuan Yang, Chau-Jong Wang (2013). Nelumbo nucilfera

leave extracts 2-acetylaminofluorene-induced liver cancer in rats . The 28th Joint

Annual Conference of Biomedical Science. 本人為通訊作者.

14.   

Chang-Che Chen, Jeng-Dong Hsu, Sen-Fa Wang, Men-Yuan Yang, Erh-Shyh

Kao, Chau-Jong Wang (2012). Hibiscus sabdariffa extracts (HSE) inhibit

atherosclerosis in cholesterol-fed rabbit. The Seventeenth Joint Annual

Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

15.   

Chang-Chieh Tang, Yu-Hsien Tang, Mon-Yuan Yang, Chau-Jong Wang (2012).

Mulberry water extracts attenuate the fatty metamorphosis in ethanol diets-fed

mice model . The 27th Joint Annual Conference of Biomedical Science, Taipei,

ROC. 本人為通訊作者.

16.   

Chi-Nan Hung, Chau-Jong Wang, Hui-Pei Huang (2012). Sulforaphane inhibits

smooth muscle cell proliferation and migration by reduction of MMP-9 activity

via Ras/PI3K pathway. The 27th Joint Annual Conference of Biomedical

Science, Taipei, ROC.

17.   

Ching-Chun Chen, Chun-Hua Chang, Chau-Jong Wang (2012). Anti-matastatic

effect of H. polyphenol-rich extracts (HPE) on human colon cancer. The71st

Annual Meeting of the Japanese Cancer Association, Sapporo, Japan. 本人為通

訊作者.

18.   

Chun-Hua Chang, Mon-Yuan Yang, Chau-Jong Wang (2012). Nelumbo Nucifera

Leaf extract (NLE) suppresses angiogenesis through the inhibition of CTGF in

human breast cancer. The71st Annual Meeting of the Japanese Cancer

Association, Sapporo, Japan. 本 人為通訊作者.

19.   

Chun-Hua Chang, Mon-Yuan Yang, Li-Chu Chen, Chau-Jong Wang (2012).

Nelumbo nucifera leaf extract (NLE) inhibits angiogenesis in human breast

cancer. The 27th Joint Annual Conference of Biomedical Science, Taipei, ROC.

本人為通訊作者.

20.   

Hsing-You Jao, Chau-Jong Wang, Huei-Jane Lee (2012). Effect of Mulberry

water extracts Improve Osteoporosis of Ovariectomic Rat. International

Conference and Exhibition on Nutraceuticals and Functional Foods, Kona,

Hawaii. USA.

21.   

Hui-Pei Huang, Sz-Ya Shao, Chi-Nan Hung, Chau-Jong Wang (2012). Mulberry

anthocyanins inhibit tumor-associated macrophage enhanced human gastric

cancer migration and angiogenesis. The 27th Joint Annual Conference of

Biomedical Science, Taipei, ROC. 本人為通訊作者.

22.   

Jing-Hsien Chen, Chau-Jong Wang, Chen-Chien Wang, Chia-Liang Lin, Hui-

Hsuan Lin (2012). Hibiscus sabdariffa leaf reduces the development of

atherosclerosis via inhibition of LDL oxidation and foam cell formation. The

27th Joint Annual Conference of Biomedical Science, Taipei, ROC.

23.   

Mon-Yuan Yang, Chau-Jong Wang (2012). Mulberry leaf extract ameliorate

obesity induced by high-fed diet in C57B1/6 mice. The 27th Joint Annual

Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

24.   

Sz-Ya Shao, Chau-Jong Wang, Hui-Pei Huang (2012). Mulberry anthocyanins

induce cell cycle arrest and apoptosis in leukemia WEHI-3 cells. The 27th Joint

Annual Conference of Biomedical Science, Taipei, ROC.

25.   

Wan-Ling Zeng, Chau-Jong Wang, Yun-Ching Chang (2012). Anthocyanins:

Evaluation of the in vitro. The 27th Joint Annual Conference of Biomedical

Science, Taipei, ROC.

26.   

Chau-Jong Wang, Ya-Ping Lin, Huei-Jane Lee (2011). Mulberry water extract

improve osteoporosis in ovariectomic rat. International Conference on Food

Factors, Taipei, ROC. 本人為第一作者.

27.   

Chi-Nan Hung, Hui-Pei Huang, Chau-Jong Wang (2011). Chemoinhibitory

Effect of sulforaphane on Smooth muscle cell Proliferating and Migration

Involved in the Ras/PI3K Pathway. International Conference on Food Factors,

Taipei, ROC. 本人為通訊作者.

28.   

Chun-Hua Chang, Jih-Shin Peng, Mon-Yuan Yang, Chau-Jong Wang (2011).

Protection effect of mulberry extract in STZ inducing rat liver injury involves

attenuation hepatic lipid accumulation. The 26th Joint Annual Conference of

Biomedical Science, Taipei, ROC. 本人為通訊作者.

29.   

Chun-Hua Chang, Mon-Yuan Yang, Chau-Jong Wang (2011). Nuciferine Leaf

extract (NLE) inhibits human breast cancer growth by suppressing fatty acid

synthase and Akt signaling. 70th Annual Meeting of the Japanese Cancer

Association, Nagoya, Japan. 本 人為通訊作者.

30.   

Hsing-You Jao, Chau-Jong Wang, Xiu-Juan Zhan, Huei-Jane Lee (2011).

Mulberry water extracts ameliorate diabetic cataract in type diabetes animal

model. International Conference on Food Factors, Taipei, ROC.

31.   

Hui-Hsuan Lin, Chau-Jong Wang, Jing-Hsien Chen (2011). Apoptotic effect of

Hibiscus sabdariffa leaf on human prostate cancer cells through both intrinsic

and extrinsic pathways. International Conference on Food Factors, Taipei, ROC.

32.   

Hui-Pei Huang, Chau-Jong Wang (2011). The mechanism of MACs inhibiting

macrophage enhanced gastric cancer migration and angiogenesis. International

Conference on Food Factors, Taipei, ROC. 本人為通訊作者.

33.   

Hui-Pei Huang, Chau-Jong Wang (2011). Cyanidine-rich Mulberry anthocyanins

induces apoptosis and suppresses growth in nude mice xenografts. The 26th Joint

Annual Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

34.   

Hui-Pei Huang, Horng-Rong Chang, Chau-Jong Wang (2011). Aristolochic acid

enhances the invasion/migration of human urothelial cancer TSGH cells. The

26th Joint Annual Conference of Biomedical Science, Taipei, ROC. 本人為通訊

作者.

35.   

Hui-Pei Huang, Yun-Ching Chang, Chi-Nan Hung, Chau-Jong Wang (2011).

Cyanidine-rich Mulberry anthocyanins inhibit the AGS gastric cancer cell

growth in vitro and xenograft mice via p38/p53 and c-jun signaling. International

Conference on Food Factors, Taipei, ROC. 本人為通訊作者.

36.   

Jeng-Rong Lin, Cheng-Ying Wu, Hsiang-Yu Chang, Jing-Hsien Chen, Chau-

Jong Wang, Jen-Kun Lin, Hui-Hsuan Lin (2011). High Glucose-Induced Insulin

Signaling Blockade in Human HepG2 Hepatoma Cells. The 26th Joint Annual

Conference of Biomedical Science, Taipei, RO

37.   

Jing-Hsien Chen, Chau-Jong Wang, Hui-Hsuan Lin (2011). Inhibition of

Benzo(a)pyrene-Induced Forestomach Tumors by Hibiscus Sabdariffa Linne.

The 26th Joint Annual Conference of Biomedical Science, Taipei, ROC.

38.   

Jing-Hsien Chen, Chau-Jong Wang, Hui-Hsuan Lin (2011). Chemopreventive

effects of Hibiscus sabdariffa Linne leaf extract on prostate cancer cells through

apoptosis induction. The 26th Joint Annual Conference of Biomedical Science,

Taipei, ROC.

39.   

Mon-Yuan Yang, Chau-Jong Wang (2011). Morus alba L. leaves extract inhibits

the development of atherosclerosis in cholesterol-fed rabbits. The 26th Joint

Annual Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

40.   

Mon-Yuan Yang, Kuei-Chuan Chan, Chau-Jong Wang (2011). Mulberry leaf

polyphenols possess antiatherogenesis effect via inhibiting VAMC proliferation

and migration. International Conference on Food Factors, Taipei, ROC. 本人為

通訊作者.

41.   

Mon-Yuan Yang, Li-Chu Chen, Chau-Jong Wang (2011). Polyphenol-enriched

extracts from Nelumbo Nucifera leave suppress the migration and invasion in

breast cancer cell. 70th Annual Meeting of the Japanese Cancer Association,

Nagoya, Japan. 本人為通訊作者.

42.   

Mon-Yuan Yang, Pei-Jun Chung, Chau-Jong Wang (2011). Solanum nigrum L.

polyphenolic extract suppresses angiogenesis-mediated tumor growth through

inhibition of AKT/mammalian target of rapamycin pathway. The 26th Joint

Annual Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

43.   

Xiu-Juan Zhan, Hsing-You Jao, Chau-Jong Wang, Huei-Jane Lee (2011).

Mulberry water extract ameliorate diabetes complicated nephropathy and

osteoporosis in animal model. International Conference and Exhibition on

Nutraceuticals and Functional Foods, Sapporo, Japan.

44.   

Chih-Ying Wang, Chau-Jong Wang, Huei-Jane Lee (2010). The ameliorative

effect of apple polyphenol on streptozotocin induced diabetic nephropathy. The

25th Joint Annual Conference of Biomedical Science, Taipei, ROC.

45.   

Chin-Hsing Feng, Chau-Jong Wang, Fu-Yuan Hsueh, Tung-hsi Yu (2010).

Resveratrol protect the brain sod sustained epileptic activity in the pilocarpineinduced

changes in the next. The 25th Joint Annual Conference of Biomedical

Science, Taipei, ROC.

46.   

Huei-Jane Lee, Chau-Jong Wang (2010). Gallic acid induced apoptosis and

autophagy in bladder cancer cell. AACR 101st Annual Meeting, USA. 本人為通

訊作者.

47.   

Hui-Hsuan Lin, Jing-Hsien Chen, Chau-Jong Wang (2010). Induction of

apoptosis in the lung tissue from rats to cigarette smoke involves p38/JNK

MAPK pathway. The 25th Joint Annual Conference of Biomedical Science ,

Taipei, ROC. 本人為通訊作者.

48.   

Man-Jung Hsu, Mon-Yang Yang, Chau-Jong Wang (2010). Mulberry

polyphenolic components reduce hepatic lipid accumulation via inhibiting

lipogenesis and hepatic clearance. The 25th Joint Annual Conference of

Biomedical Science, Taipei, ROC. 本人為通訊作者.

49.   

Yun-Ching Chang, Chau-Jong Wang (2010). Inhibitory effects of the water

extract of Nelumbo Nucifera leaf on human breast carcinoma MCF-7 cells in

vitro and in vivo. AACR 101st Annual Meeting, USA. 本人為通訊作者.

50.   

Chen-Shu Chun, Yun-Ching Chang, Chau-Jong Wang (2009). Mulberry leave

polyphenols reduced lipid accumulation in hepatocytes. The 24th Joint Annual

Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

51.   

Cheng-Hsun Wu, Chun-Huz Chang, Yuan-Wei Shin, Ting-Tsz Ou, Chi-Chou

Huang, Jeng-Dong Hsu, Chau-Jong Wang (2009). EP4 upregulation of ras

signaling and feedback regulation of ras in human colon tissue and cancer cells.

The 5th International Congress of Asian Society of Toxicology, Taipei, ROC.

人為通訊作者.

52.   

Chin-Hsing Feng, Chau-Jong Wang, Mei-Lin Shen, Ching-Huei Lin, Hsieh Pei-F

(2009). Effect of Resveratrol Prevents Neuronal Damage in Pilocarpine-induced

Status Epilepticus. The 24th Joint Annual Conference of Biomedical Science,

Taipei, ROC.

53.   

Chin-Ya Wang, Mon-Yuan Yang, Ming-Chen Lin, Chau-Jong Wang (2009).

Rutin-rich Nelumbo Nucifera leaves extract diminish heaptic lipids accumulation

through AMPK phosphorylation and PPARγ expression. The 24th Joint Annual

Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

54.   

Dun-Hao Wu, Cing-Yuan Chen, Chau-Jong Wang (2009). Chemoinhibitory

effect of solanum nigrum water extracts on the angiogenesis and metastasis in

B16 melanoma cells. The 24th Joint Annual Conference of Biomedical Science,

Taipei, ROC. 本人為通訊作者.

55.   

Horng-Rong Chang, Hui-Pei Huang, Jong-Da Lian, Sheng-Wen Wu, Tung-Wei

Hung, Chau-Jong Wang (2009). Aristolochic acid enhances the

invasion/migration of human urothelial cancer TSGH cells. Annual Conference

of Taiwan Society Nephrology, Taipei, ROC. 本人為通訊作者.

56.   

Hui-Hsuan Lin, Jing-Hsien Chen, Chau-Jong Wang (2009). Hibiscus polyphenolrich

extract induces G1 phase cell cycle arrest in human gastric cells. The 24th

Joint Annual Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

57.   

Jing-Hsien Chen, Hui-Hsuan Lin, Tai-An Chiang, Yi-Chieh Lee, Chau-Jong

Wang (2009). Gaseous Nitrogen Oxide Promotes Human Lung Cancer Cell Line

A549 Migration amd Invasion via JNK1/p38 MAPK and PI3K-Akt pathways.

The 24th Joint Annual Conference of Biomedical Science, Taipei, ROC. 本人為

通訊作者.

58.   

Sheng-You Liao, Hsieh-Hsun Ho, Wei-Chi Ho and Chau-Jong Wang (2009).

Gallic acid inhibit gastric cancer metastasis via inhibition of RHOB expression

and downregulation of migration signals. The 24th Joint Annual Conference of

Biomedical Science, Taipei, ROC. 本人為通訊作者.

59.   

Shu-Ling Huang, Mon-Yuan Yang,Chung-Chia Liao, Chau-Jong Wang (2009).

Caffeic acid regulates binding protein-1c expression and its downstream target

genes. The 24th Joint Annual Conference of Biomedical Science, Taipei, ROC.

本人為通訊作者.

60.   

Ting-Tzu Ou, Huei-Jane Lee, Chau-Jong Wang (2009). Gallic acid induced cell

cycle arrest at G2/M phase via regulating checkpoint kinase 1-mediated

phosphorylation of Cdc25C in bladder cancer cell. The 24th Joint Annual

Conference of Biomedical Science, Taipei, ROC. 本人為通訊作者.

61.   

Yi-Ming Kuo, Chao-Hsin Lee, Chau-Jong Wang, Huei-Jane Lee (2009). Aqueous

extract from solanum nigrumi ameliorates neurodegeneration in experimental

parkinson disease. The 24th Joint Annual Conference of Biomedical Science,

Taipei, ROC.

(C) Patent

1.

專利名稱: 洛 神花萃取物用於製備腦心血管病變藥物的用途
國別: 大陸
專利號碼: ZL 011 42452,4

2.

專利名稱: 洛 神花萼萃取物用於製備抑制腦心血管病變之藥物用途
國別: 台灣
專利號碼: 發明第I 38882

3.

專利名稱: METHOD TO COUNTER OXIDATION OF LDL,DECREASE TRIGLYCERIDE OR CHOLESTEROL AND INHIBIT ATHEROSCLEROSIS
國別: 美國
專利號碼: US 6,849,278 B2

4.

專利名稱: EXTRACTS OF SACRED WATER LOTUS FOR THE TREATMENT OF CANCER
國別: 美國
專利號碼: US 7,662,413 B2

5.

專利名稱: 洛 神花青素抗血癌之用途
國別: 美國
專利號碼:US 8,007,835 B2

6.

專利名稱: 治 療癌症之水萃荷葉萃取物
國別:台灣
專利號碼:發明第I406667



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