生化暨生物科技研究所 -- 許立松 老師
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許立松 老師

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許立松 副教授

Li-Sung Hsu

          聯絡方式  
    專長介紹

學歷:

國立陽明醫學院醫事技術系 學士(75年8月至79年7月)

國防醫學院生物化學研究所 碩士(80年8月至82年6月)

國防醫學院生命科學研究所 博士(83年8月至89年6月)

經歷:

中央研究院生物醫學研究所 博士後研究員 2000年9月至2001年2月
輔英技術學院醫事技術系 助理教授 2001年2月至2002年7月
中山醫學大學生化所 助理教授 2002年8月至2012年1月

現任:

中山醫學大學生化所 副教授 2012年2月至今

專長 訊息傳遞、分子腫瘤學

研究:

1. 研究CaMKK基因調控及其結合蛋白
2. 研究14-3-3基因調控及生物功能
 


聯絡電話:04-24730022-11682
E-mail:lsh316@csmu.edu.tw

  許立松老師的照片        
學術著作目錄
 

Publication List

1. Shang-Tao CHIEN, Chun-Hsiu LIN, Jui-Chen HSUEH, Pei-Ling LI, Chao-Hsun HSU, Shu-Hui CHANG, Hsin-I CHIEN, Ren-Jy BEN, Fu-Hsin CHANG, Li-Sung HSU Mutation of gyrA and parC in clinical isolates of Acinetobacter baumannii and its relationship with antimicrobial drugs resistance in Taiwan. Ann. Microbiol. Accepted.
2. Hwang JM, Kao SH, Hsieh YH, Li KL, Wang PH, Hsu L.S., Liu JY. Reduction of anion exchanger 2 expression induces apoptosis of human hepatocellular carcinoma cells. Mol Cell Biochem. 2009 Jul; 327(1-2):135-44
3.

Chen KM, Lee HH, Lai SC, Hsu L. S., Wang CJ, Liu JY. Apoptosis in meningoencephalitis of Angiostrongylus cantonensis-infected mice. Exp Parasitol. 2008, 119(3):385-90.

4. Wu SL, Hsu L.S., Tu WT, Wang WF, Huang YT, Pawlak CR, Ho YJ. Effects of D-cycloserine on the behavior and ERK activity in the amygdala: role of individual anxiety levels. Behav Brain Res. 2008 Mar 5;187(2):246-53.
5. Hsio, P. C., Liu, M. C., Chen, L. M., Tsai, C. Y., Wang, Y. T., Chen, J., Hsu, L. S. Promoter methylation of p16 and EDNRB gene in leukemia patients in Taiwan. The Chinese Journal of Physiology (CJP), Vol.51, No.1, Januar , 2008
6. Lee, H. C., Hsu, L. S., Yin, P. H., Lee, L. M., and Chi, C. W. Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion. Mitochondrion. 2007, 7:157-63.
7. Chen, K. M., Liu, J. Y., Lai, S. C., Hsu, L. S., and Lee, H. H. Association of plasminogen activators and matrix metalloproteinase-9 proteolytic cascade with blood-CNS barrier damage of angiostrongyliasis. Int J Exp Pathol. 2006 87:113-9.
8. Chen, S. C., Chen, C. H., Chern, C. L., Hsu, L. S., Huang, Y. C., Chung, K. T., and Chye, S. M. p-Phenylenediamine induces p53-mediated apoptosis in Mardin-Darby canine kidney cells. Toxicol In Vitro. 2006 20:801-7.
9. Chen S. C., Lin C. Y., Chen Y. H.(陳雅慧), Fang, H. Y., Cheng C. Y., Chang C. W.(張智雯), Chen, R. A., Tai, H. L.,Lee, C. H., Chou, M. C., Lin, T. S*., Hsu, L. S*.(*correspondence author). Aberrant promoter methylation of EDNRB in lung cancer in Taiwan. Oncology Reports, 2006 15:167-72.
10. Hsu, L. S.,Lee, H. C., Chau, G.. Y., Yin, P. H., Chi, C. W., Lui, W. Y. Aberrant methylation of EDNRB and p16 genes in hepacellular carcinomas (HCC) in Taiwan. Oncology Reports, 2006 15:507-11.
11. Chen, K. M., Liu, J. Y., Lai, S. C., Hsu, L. S., Lee, H. H. Association of plasminogen activators and matrix metalloproteinase-9 proteolytic cascade with blood-CNS barrier damage of angiostrongyliasis. Int. J. Exp. Path. 2006, 87: 113-9.
12. Chang, H. R., Cheng, T. L., Liu, T. Z., Hu, H. S., Hsu, L. S., Tseng, W. C., Chen, C. H., Tsao, D. A. Genetic and cellular characterizations of human TCF4 with microsatellite instability in colon cancer and leukemia cell lines. Cancer Lett. 2006, 223:165-71.
13. Ho, Y. J., Hsu, L. S., Wang, C. F., Hsu, W. Y., Lai, T. J., Hsu, C. C., Tsai, C. F. Behavioral effects of d-cycloserine in rats: the role of anxiety level. Brain Res. 2005; 1043:179-185
14. Hsu, L. S., Lee, H. H., Chen, K. M., Chou, H. L., and Lai, S. C. Matrix metellopreteinase –1 and –9 in the granulomatous fibrosis of rat infected with Angiostrogylus cantonesis. Annals of Tropical Medicine and Parasiotology 2005; 99: 61-70
15. Wu, L. T., Chu, C. C., Chung, J. G., Chen, C. H., Hsu, L. S., Liu, J. K., Chen, S. C. Effects of tannic acid and its related compounds on food mutagens or hydrogen peroxide-induced DNA strands breaks in human lymphocytes. Mutation Research 2004; 22:556:75-82.
16. Promoter methylation of EDNRB and DLC-1 genes in lung cancer in Taiwan. Changhua J. Med. Oct 9 (4): 191-195. (equally contributed with first author)Chang, F. H., Tzeng, D. S., Lee, T. M., Chen, T. C, Hsu, L. S., Lung, F. W. Mutations in the p53 tumor suppressor gene in colorectal cancer in Taiwan. Kaohsiung J Med Sci. 2003 Apr;19(4):151-8.
17. Hsu, L. S., Chen, G. D., Lee, L. S., Chi, C. W., Cheng, J. F., Chen, J. Y.Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity. J Biol Chem. 2001 Aug 17; 276 (33): 31113-23. (SCI)
18. Hsu, L. S., Tsou, A. P., Chi, C. W., Lee, C. H., Chen, J.Y.Cloning, expression and chromosomal localization of human Ca2+/calmodulin-dependent protein kinase kinase. J Biomed Sci. 1998;5(2):141-9. (SCI)
19. Lee, C. H., Hsu, L. S., Chi, C. W., Chen, G. D., Yang, A. H., Chen, J. Y.High frequency of rearrangement of the RET protooncogene (RET/PTC) in Chinese papillary thyroid carcinomas. J Clin Endocrinol Metab. 1998 May;83(5):1629-32. (SCI).
20. Hsu, L. S., Chou, W. Y., Chueh, S. H.Evidence for a Na+/Ca2+ exchanger in neuroblastoma x glioma hybrid NG108-15 cells. Biochem J. 1995 Jul 15;309 ( Pt 2):445-52. (SCI)
21. Chueh, S. H., Hsu, L. S., Song, S. L.Two distinct ATP signaling mechanisms in differentiated neuroblastoma x glioma hybrid NG108-15 cells. Mol Pharmacol. 1994 Mar;45(3):532-9. (SCI)

 

   
  
 


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